Preferred Label : Ceftazidime/Avibactam Sodium;
NCIt synonyms : Ceftazidime-Avibactam Sodium; CAZ-AVI;
NCIt definition : A combination preparation containing the third-generation cephalosporin ceftazidime
and the sodium salt form of avibactam, a non-beta-lactam beta-lactamase inhibitor,
with antibiotic and beta-lactamase inhibiting activity, respectively. Upon administration,
ceftazidime binds to essential penicillin-binding proteins (PBPs) and inhibits cell
wall synthesis in certain bacteria. Avibactam binds to and inactivates beta-lactamases,
thereby protecting ceftazidime from degradation and increasing ceftazidime's efficacy.;
Drug name : Avycaz;
Origin ID : C127836;
UMLS CUI : C4287586;
Semantic type(s)
- concept_is_in_subset
