Vinepidine - CISMeF

Preferred Label : Vinepidine;

NCIt synonyms : 4'-Deoxyepivincristine;

NCIt definition : A vinca alkaloid compound and semi-synthetic vincristine derivative with antineoplastic activity. Vinepidine binds to and stabilizes tubulin, thereby preventing tubulin polymerization and depolymerization, which result in microtubule assembly and disassembly, respectively. Treated cells are unable to complete mitosis process and are arrested in the metaphase, thereby leading to an inhibition of cell growth.;

UNII : W3375J6V0Y;

InChIKey : KLFUUCHXSFIPMH-LMQWBHQESA-N;

CAS number : 68170-69-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 68170-69-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C46H56N4O9;

Details

Origin ID

C1274;

UMLS CUI

C0078255;

Currated CISMeF NLP mapping
- vinepidine [MeSH concept]
- vinepidine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- vinepidine [MeSH concept]
- vinepidine [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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