IGHV3-21 wt Allele

Preferred Label : IGHV3-21 wt Allele;

NCIt synonyms : VH; Homo sapiens Immunoglobulin Heavy Variable 3-21 Gene; Immunoglobulin Heavy Variable 3-21 wt Allele; IGHV321; Immunogloblin Heavy Chain Variable Region 3-21 Gene;

NCIt definition : Human IGHV3-21 wild-type allele is located in the vicinity of 14q32.33 and is approximately 1 kb in length. This allele, which encodes the immunoglobulin heavy variable 3-21 protein, plays a role in the structure of immunoglobulin heavy chains. Expression of mutated IGHV3-21 in chronic lymphocytic leukemia may be associated with a poor prognosis.;

NCIt note : There are 4 alleles of the IGHV3-21 gene.;

NCI Metathesaurus CUI : CL508159;

GenBank Accession Number : Z14073;

Details

Origin ID

C127014;

UMLS CUI

C4284744;

Automatic exact mappings (from CISMeF team)
- Vaginal hysterectomy (procedure) [SNOMED CT concept]
- Vitreous haemorrhage [ICD-11 Category]
- immunoglobulin heavy variable 3-21 [ORDO Gene]
- urinary bladder, overactive [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 14q32.33 [NCIt concept]
gene_plays_role_in_process
- Humoral Immunity [NCIt concept]
- Immune System Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients