MICA wt Allele

Preferred Label : MICA wt Allele;

NCIt synonyms : Major Histocompatibility Class I Chain-Related Gene A; MHC Class I Polypeptide-Related Sequence A wt Allele; MIC-A; PERB11.1;

NCIt definition : Human MICA wild-type allele is located in the vicinity of 6p21.3 and is approximately 16 kb in length. This allele, which encodes MHC class I polypeptide-related sequence A protein, is involved in natural killer cell inhibition. Variation of the gene may be associated with increased susceptibility to psoriasis 1 and psoriatic arthritis.;

NCI Metathesaurus CUI : CL508039;

GenBank Accession Number : L14848;

Details

Origin ID

C126960;

UMLS CUI

C4284187;

Automatic exact mappings (from CISMeF team)
- Major histocompatibility complex class I chain-related gene a [OMIM gene]
- Mica [DeCS]
- Mica [DeCS]
- Mica (substance) [SNOMED CT concept]
- mica [Substance BNPC]
- mica [MeSH concept]
- mica [MeSH Supplementary Concept]
- mica [SNOMED Notion]
OMIM relation
- Major histocompatibility complex class I chain-related gene a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.3 [NCIt concept]
gene_is_element_in_pathway
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
gene_plays_role_in_process
- Antigen Binding [NCIt concept]
- Antimicrobial Effect [NCIt concept]
- Immune System Process [NCIt concept]
- NK Cell Activation [NCIt concept]
- Receptor Binding [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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