SELENOF wt Allele

Preferred Label : SELENOF wt Allele;

NCIt synonyms : 15 kDa Selenoprotein Gene; Selenoprotein F wt Allele; Selenoprotein, 15-kD Gene; SEP15; Selenoprotein F (15kDa) Gene;

NCIt definition : Human SELENOF wild-type allele is located in the vicinity of 1p22.3 and is approximately 52 kb in length. This allele, which encodes selenoprotein F, may be involved in protein folding.;

NCIt note : Selenium is found not as a cofactor in mammalian proteins but as a selenocysteine residue, which is encoded by UGA. In order for the UGA codon to be translated as a selenocysteine rather than a stop codon, a stem-loop structure called a selenocysteine insertion sequence (SECIS) must be present in the 3' untranslated region (UTR) of the selenoprotein mRNA. (OMIM);

NCI Metathesaurus CUI : CL508107;

GenBank Accession Number : NM_004261;

Details

Origin ID

C126954;

UMLS CUI

C4288263;

Automatic exact mappings (from CISMeF team)
- Selenoprotein f [OMIM gene]
OMIM relation
- Selenoprotein f [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Ligand Binding [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Protein Folding [NCIt concept]

Keyword's position in hierarchy(ies) :

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