Type 1 Regulatory T-Cell

Preferred Label : Type 1 Regulatory T-Cell;

NCIt synonyms : Tr1 Cell; T Regulatory Cell 1; Type 1 T reg; Tr1; Type 1 Treg; Type-1 T Regulatory Cell; Type 1 Regulatory T Lymphocyte; Type 1 Regulatory T Cell; Type 1 Regulatory T-Lymphocyte;

NCIt definition : A population of CD4 , CD25-, and FoxP3- T-lymphocytes that are involved in immunotolerance. These cells secrete the immunosuppressive cytokines, tumor growth factor-beta (TGF-B) and interleukin-10, and may induce cell cycle arrest or apoptosis in effector T-cells.;

Details

Origin ID

C126755;

UMLS CUI

C4284002;

Anatomic structure is physical part of
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
Associated anatomy of gene products
- Interleukin-35 [NCIt concept]
Automatic exact mappings (from CISMeF team)
- TNF receptor superfamily member 11b [ORDO Gene]
- Thioredoxin reductase 1 [OMIM gene]
- Tr1 cells [MeSH concept]
- t-lymphocytes, regulatory [MeSH Descriptor]
Semantic type(s)
- Cell [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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