Preferred Label : 2,6-Dimethoxyquinone;
NCIt synonyms : p-Benzoquinone, 2,6-Dimethoxy-; 2,6-Dimethoxy-1,4-Benzoquinone; 2,5-Cyclohexadiene-1,4-Dione, 2,6-Dimethoxy- (9CI); 2,6-Dimethoxy-p-Benzoquinone; 2,6-Dimethoxycyclohexa-2,5-Diene-1,4-Dione; 2,6-Dimethoxy-p-Quinone; 2,5-Cyclohexadiene-1,4-Dione, 2,6-Dimethoxy-; 2,6-DMBQ; 2,6-Dimethoxybenzoquinone;
NCIt definition : A methoxy-substituted benzoquinone and bioactive compound found in fermented wheat
germ extracts, with potential antineoplastic and immune-enhancing activity. 2,6-Dimethoxyquinone
(2,6-DMBQ) inhibits anaerobic glycolysis thereby preventing cellular metabolism and
inducing apoptosis. As cancer cells use the anaerobic glycolysis pathway to metabolize
glucose and cancer cells proliferate at an increased rate as compared to normal, healthy
cells, this agent is specifically cytotoxic towards cancer cells. In addition, 2,6-DMBQ
exerts immune-enhancing effects by increasing natural killer (NK) cell and T-cell
activity against cancer cells.;
UNII : 1Z701W789S;
CAS number : 530-55-2;
Origin ID : C126754;
UMLS CUI : C0045611;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
