Fluoroquinolone Antibiotic

Preferred Label : Fluoroquinolone Antibiotic;

NCIt synonyms : Fluoroquinolones; Fluoroquinolone;

NCIt definition : Any quinolone antibiotic with a fluorine (F) atom attached to the quinolone structure, with broad-spectrum antibacterial activity. Fluoroquinolones diffuse through the bacterial cell wall and act by inhibiting bacterial topoisomerase II, DNA gyrase and/or bacterial topoisomerase IV, which are enzymes involved in bacterial DNA replication. This prevents DNA replication and leads to a blockage of bacterial cell proliferation.;

Details

Origin ID

C126712;

UMLS CUI

C0949665;

Automatic exact mappings (from CISMeF team)
- Fluoroquinolones [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Fluoroquinolone [LOINC component]
- Fluoroquinolone (substance) [SNOMED CT concept]
- fluoroquinolones [MeSH Descriptor]
- fluoroquinolones [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Fluoroquinolone [LOINC component]
- Fluoroquinolone (substance) [SNOMED CT concept]
- fluoroquinolones [MeSH Descriptor]
- fluoroquinolones [MeSH concept]
Validated automatic mappings to BTNT
- fluoroquinolones [ATC Code]
- fluoroquinolones [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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