Preferred Label : BCG Tokyo-172 Strain Solution;
NCIt synonyms : Bacillus Calmette-Guerin Tokyo-172 Strain Solution;
NCIt related terms : BACILLUS CALMETTE-GUERIN SUBSTRAIN TOKYO 172-1 LIVE ANTIGEN; BCG Tokyo-172 Strain Vaccine;
NCIt definition : A solution containing an attenuated, live culture preparation of the bacillus Calmette-Guerin
(BCG) strain of Mycobacterium bovis obtained from the Pasteur Institute in 1924, with
potential immunostimulating and antineoplastic activities. Although the precise mechanism
of action is unknown, upon intravesical instillation through a catheter, the attenuated,
live BCG bacteria in the BCG Tokyo-172 strain solution come into direct contact with
the bladder wall and elicits a local, multifaceted immune response against the BCG
antigens, which kills the bladder cancer cells. Previous vaccination with a systemic
BCG vaccine may enhance the immune system's response against the BCG antigens.;
UNII : 267H8I71ZT;
Drug name : Immunobladder;
NCI Metathesaurus CUI : CL508158;
Origin ID : C126694;
UMLS CUI : C4289943;
Semantic type(s)
- concept_is_in_subset
