DFFB wt Allele

Preferred Label : DFFB wt Allele;

NCIt synonyms : DFF2; DNA Fragmentation Factor Subunit Beta wt Allele; CPAN; DNA Fragmentation Factor, 40kDa, Beta Polypeptide (Caspase-Activated DNase) Gene; DFF40; DFF-40; CAD; Deoxyribonuclease III, Caspase-Activated Gene; DNA Fragmentation Factor, 40-kD, Beta Subunit Gene;

NCIt definition : Human DFFB wild-type allele is located in the vicinity of 1p36.3 and is approximately 28 kb in length. This allele, which encodes DNA fragmentation factor subunit beta protein, plays a role in the regulation of DNA fragmentation and chromosome condensation during apoptosis.;

NCI Metathesaurus CUI : CL505026;

GenBank Accession Number : NM_001282669;

Details

Origin ID

C126526;

UMLS CUI

C4284121;

Automatic exact mappings (from CISMeF team)
- Carbamoyl phosphate synthetase/aspartate transcarbamylase/dihydroorotase [OMIM gene]
- Cold agglutinin disease [ORDO Disease]
- Computer aided design [UNESCO concept]
- Coronary atherosclerosis [ICD-11 Category]
- Dna fragmentation factor, 40-kd, beta subunit [OMIM gene]
- carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [ORDO Gene]
- computer-aided design [MeSH Descriptor]
- coronary artery disease [MedlinePlus Topic]
- diagnosis, computer-assisted [EFMI term]
- diagnosis, computer-assisted [MeSH Descriptor]
OMIM relation
- Dna fragmentation factor, 40-kd, beta subunit [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1p36.3 [NCIt concept]
gene_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- Apoptotic DNA Fragmentation Pathway [NCIt concept]
- Caspase Cascade Pathway [NCIt concept]
- DR3 and DR4/5 Mediated Apoptosis Pathway [NCIt concept]
- Fas Signaling Pathway BioCarta [NCIt concept]
- Granzyme A Mediated Apoptosis Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- Mitochondria in Apoptotic Signaling Pathway [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Fragmentation [NCIt concept]
- Hydrolysis [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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