ZFTA wt Allele

Preferred Label : ZFTA wt Allele;

NCIt synonyms : C11orf95; MGC3032; Chromosome 11 Open Reading Frame 95 Gene; Zinc Finger Translocation Associated wt Allele;

NCIt definition : Human ZFTA wild-type allele is located in the vicinity of 11q13.1 and is approximately 9 kb in length. This allele, which encodes zinc finger translocation-associated protein, may play a role in transcriptional regulation. A chromosomal aberration, t(11;16)(q13;p13), involving this gene and the MRTFB (MKL2) gene may be associated with chondroid lipomas. A chromosomal aberration involving chromothripsis of the long arm of chromosome 11 causes fusions of this gene and the RELA gene and is associated with more than two-thirds of supratentorial ependymomas.;

NCI Metathesaurus CUI : CL505019;

GenBank Accession Number : BC000572;

PubMed : 24553141; 20607705;

Details

Origin ID

C126513;

UMLS CUI

C4284743;

Automatic exact mappings (from CISMeF team)
- Zinc finger translocation-associated protein [OMIM gene]
- zinc finger translocation associated [ORDO Gene]
OMIM relation
- Zinc finger translocation-associated protein [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q13.1 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Supratentorial Ependymoma ZFTA Fusion-Positive [NCIt concept]
gene_plays_role_in_process
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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