" /> Anti-FGFR4 Monoclonal Antibody U3-1784 - CISMeF





Preferred Label : Anti-FGFR4 Monoclonal Antibody U3-1784;

NCIt definition : A human monoclonal antibody against human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, U3-1784 specifically binds to and blocks FGFR4. This prevents the activation of FGFR4, inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells. FGFR4, a receptor tyrosine kinase overexpressed by certain tumor cell types, is involved in tumor cell proliferation, differentiation, angiogenesis, and survival.;

Molecule name : U3 1784; U3-1784;

NCI Metathesaurus CUI : CL504900;

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27/05/2024


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