High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements

Preferred Label : High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements;

NCIt synonyms : Double-Hit Lymphoma; Double Hit Lymphoma; DH Lymphoma; DHL; High-Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements; HGBCL-DH;

NCIt related terms : double_hit_lymphoma;

NCIt definition : High-grade B-cell lymphoma characterized by the abnormal rearrangement of two genes, MYC gene and either BCL2 or BCL6 genes. Patients with this type of lymphoma usually respond poorly to standard treatments and have a poor prognosis.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL504553;

Détails

Origin ID

C125904;

UMLS CUI

C4285066;

Automatic exact mappings (from CISMeF team)
- Double hit lymphoma [MedDRA Preferred Term]
- High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements [ICD-11 Extension code]
- High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) [SNOMED CT concept]
- High grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement [ORDO Disease]
- High-grade B-cell lymphoma, with MYC and BCL2 and/or BCL6 rearrangements [MedDRA LLT]
- high-grade B-cell lymphoma double-hit/triple-hit [DO Concept]
Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- EBV-Transformed Mature B-Lymphocyte [NCIt concept]
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- MYC Gene Rearrangement [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Double hit lymphoma [MedDRA Preferred Term]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- GDC Property Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Diffuse Pattern [NCIt concept]
- Double Hit Lymphoproliferative Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- MYC Gene [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients