NCIt definition : A human monoclonal antibody against the carbohydrate antigen sialyl-Lewis A (carbohydrate
antigen 19-9; CA19-9), with potential antineoplastic activity. Upon administration,
monoclonal antibody 5B1 binds to CA19-9 and kills CA19-9-expressing tumor cells, possibly
through the induction of both complement-dependent cytotoxicity (CDC) and antibody-dependent
cell-mediated cytotoxicity (ADCC). CA19-9 is overexpressed on a number of different
tumor cell types, and plays a key role in tumor cell survival and metastasis.;
UNII : KEX1QY18OH;
CAS number : 2101410-19-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2101410-19-7
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G-SRS /a ;
Semantic type(s)