" /> Anti-CA19-9 Monoclonal Antibody BNT321 - CISMeF





Preferred Label : Anti-CA19-9 Monoclonal Antibody BNT321;

NCIt synonyms : HuMab-5B1; HuMab 5B1; Anti-CA19-9 Monoclonal Antibody 5B1;

NCIt related terms : MVT-5873;

NCIt definition : A human immunoglobulin G1 (IgG1) monoclonal antibody directed against the carbohydrate antigen sialyl Lewis A (carbohydrate antigen 19-9; CA19-9), with potential antineoplastic activity. Upon administration, anti-CA19-9 monoclonal antibody BNT321 targets and binds to CA19-9, and kills CA19-9-expressing tumor cells through the induction of both complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC). CA19-9 is overexpressed on a number of different tumor cell types, and plays a key role in tumor cell survival and metastasis.;

UNII : KEX1QY18OH;

CAS number : 2101410-19-7;

Molecule name : 5B1; MVT-5873; BNT 321; BNT-321;

NCI Metathesaurus CUI : CL504549;

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09/05/2025


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