Recurrent Acute Myeloid Leukemia, Myelodysplasia-Related

Preferred Label : Recurrent Acute Myeloid Leukemia, Myelodysplasia-Related;

NCIt synonyms : Recurrent Myelodysplastic Syndrome; Relapsed or Refractory High-Risk Myelodysplastic Syndrome; Recurrent HRMDS; Relapsed or Refractory HRMDS; Recurrent Acute Myeloid Leukemia with Myelodysplasia-Related Changes;

NCIt related terms : Recurrent Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes;

NCIt definition : The reemergence of acute myeloid leukemia, myelodysplasia-related after a period of remission.;

Neoplastic status : Malignant;

Details

Origin ID

C125715;

UMLS CUI

C4086782;

Disease excludes abnormal cell
- Neoplastic Lymphoblast [NCIt concept]
Disease excludes normal cell origin
- Lymphocyte [NCIt concept]
Disease may have findings
- Granulocytopenia [NCIt concept]
- Hypercellular Bone Marrow [NCIt concept]
- Pancytopenia [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Thrombocytosis [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
- Recurrent Genetic Abnormalities Present [NCIt concept]
- Solid Growth Pattern [NCIt concept]
- Therapy-Related Toxicity [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
- TP53 Gene Mutation [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloblast [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_finding
- Blasts 20 Percent or More of Bone Marrow Nucleated Cells [NCIt concept]
- Blasts 20 Percent or More of Peripheral Blood White Cells [NCIt concept]
- Bone Marrow Dysplasia Present in 50 Percent or More of the Cells of Two Cell Lines [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Myeloblasts 20 Percent or More of Bone Marrow Nucleated Cells [NCIt concept]
- Recurrent Disease [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 11 [NCIt concept]
- Gain of Chromosome 19 [NCIt concept]
- Gain of Chromosome 21 [NCIt concept]
- Gain of Chromosome 8 [NCIt concept]
- Gain of Chromosome 9 [NCIt concept]
- Loss of Chromosome 11q ATM Gene Locus [NCIt concept]
- Loss of Chromosome 12p [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
- del(20q11) [NCIt concept]
- del(7q11-q36) [NCIt concept]
- ins(3;3) [NCIt concept]
- inv(3)(q21.3;q26.2) [NCIt concept]
- t(3;3)(q21.3;q26.2) [NCIt concept]
- t(3;5)(q25;q34) [NCIt concept]

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