" /> Vortioxetine Hydrobromide - CISMeF





Preferred Label : Vortioxetine Hydrobromide;

NCIt synonyms : 1-(2-((2,4-Dimethylphenyl)sulfanyl)phenyl)piperazine Monohydrobromide; Piperazine, 1-(2-((2,4-dimethylphenyl)thio)phenyl)-, Hydrobromide (1:1);

NCIt definition : A hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator (SMS), with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent's purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine.;

UNII : TKS641KOAY;

InChIKey : VNGRUFUIHGGOOM-UHFFFAOYSA-N;

CAS number : 960203-27-4;

Drug name : Trintellix; Brintellix;

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07/05/2025


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