Preferred Label : Dendritic Cell-Precision Multiple Antigen T-Lymphocytes;
NCIt synonyms : DC-PMAT; Dendritic Cell-Precision Multiple Antigen T-Cells;
NCIt definition : A preparation of dendritic cell-precision multiple antigen T-cells (DC-PMAT) that
have been induced to specifically target multiple undisclosed tumor-associated antigens
(TAAs), with potential antitumor activity. Although the exact mechanism(s) of action
through which DC-PMAT cells exert their effects has yet to be elucidated, upon infusion,
these cells may stimulate the host immune system to mount a highly-specific cytotoxic
T-lymphocyte (CTL) response against tumors expressing common TAAs, which leads to
tumor cell lysis.;
NCI Metathesaurus CUI : CL504333;
Origin ID : C125634;
UMLS CUI : C4086237;
Semantic type(s)
- Cell [UMLS semantic type]
concept_is_in_subset