" /> Toremifene - CISMeF





Preferred Label : Toremifene;

NCIt synonyms : (Z)-4-Chloro-1,2-diphenyl-1[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-1-butene; (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; Farestone;

NCIt definition : A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antiestrogens. Toremifene blocks the effect of the hormone estrogen in the body. It may help control some cancers from growing, and it may delay or reduce the risk of cancer recurrence.;

UNII : 7NFE54O27T;

InChIKey : XFCLJVABOIYOMF-QPLCGJKRSA-N;

CAS number : 89778-26-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 89778-26-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C26H28ClNO;

ChEBI ID : CHEBI:9635;

Codes from synonyms : CDR0000045338; 08997; 504;

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15/05/2024


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