" /> Toremifene - CISMeF





Preferred Label : Toremifene;

NCIt synonyms : (Z)-4-Chloro-1,2-diphenyl-1[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-1-butene; (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; Farestone;

NCIt definition : A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antiestrogens. Toremifene blocks the effect of the hormone estrogen in the body. It may help control some cancers from growing, and it may delay or reduce the risk of cancer recurrence.;

UNII : 7NFE54O27T;

InChIKey : XFCLJVABOIYOMF-QPLCGJKRSA-N;

CAS number : 89778-26-7;

Chemical formula : C26H28ClNO;

ChEBI ID : CHEBI:9635;

Codes from synonyms : CDR0000045338; 08997; 504;

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28/05/2025


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