TREM2 wt Allele

Preferred Label : TREM2 wt Allele;

NCIt synonyms : Triggering Receptor Expressed On Myeloid Cells 2a Gene; Trem2a; Trem2b; Trem2c; Triggering Receptor Expressed On Myeloid Cells 2 wt Allele; TREM-2;

NCIt definition : Human TREM2 wild-type allele is located in the vicinity of 6p21.1 and is approximately 5 kb in length. This allele, which encodes triggering receptor expressed on myeloid cells 2 protein, is involved in inflammation. Expression of the gene may be associated with chronic inflammation and mutation of the gene is associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu-Hakola disease).;

GenBank Accession Number : AF213457;

Details

Origin ID

C125469;

UMLS CUI

C4085570;

Automatic exact mappings (from CISMeF team)
- Triggering receptor expressed on myeloid cells 2 [OMIM gene]
- triggering receptor expressed on myeloid cells 2 [ORDO Gene]
OMIM relation
- Triggering receptor expressed on myeloid cells 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.1 [NCIt concept]
gene_plays_role_in_process
- Immune Response Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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