Profilin-1 - CISMeF

Preferred Label : Profilin-1;

NCIt synonyms : Profilin-I; Epididymis Tissue Protein Li 184a; Profilin I;

NCIt definition : Profilin-1 (140 aa, 15 kDa) is encoded by the human PFN1 gene. This protein plays a role in the modulation of actin polymerization.;

Details

Origin ID

C125446;

UMLS CUI

C1565176;

Automatic exact mappings (from CISMeF team)
- profilin 1 [ORDO Gene]
- profilin 1 [MeSH concept]
- profilins [MeSH Descriptor]
OMIM relation
- Profilin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PFN1 protein, human [MeSH Supplementary Concept]
- PFN1 protein, human [MeSH concept]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- PFN1 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Actin Filament [NCIt concept]
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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