Thymalfasin - CISMeF

Preferred Label : Thymalfasin;

NCIt related terms : Thymosin Alpha 1;

NCIt definition : A synthetic analogue of thymosin-alpha-1, a 28-amino acid protein derived from the precursor protein prothymosin-alpha. Exhibiting a variety of immunoregulating properties, thymosin-alpha-1 induces differentiation of murine T-cell precursors and human thymocytes and the terminal differentiation of functionally immature cord blood lymphocytes and induces production of IL-2, high affinity IL-2 receptors, and B-cell growth factors by peripheral blood mononuclear cells. T-helper and cytotoxic/suppressor T-cell populations are targets of thymosin activity. Thymosin-alpha-1 has been shown to increase the efficiency of antigen presentation by macrophages and to be an endogenous modulator of alpha-thrombin activity. (NCI04);

UNII : W0B22ISQ1C;

CAS number : 62304-98-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 62304-98-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Zadaxin;

Chemical formula : C129H215N33O55;

Codes from synonyms : 09090;

Details

Origin ID

C1253;

UMLS CUI

C0076612;

Currated CISMeF NLP mapping
- Product containing thymalfasin (medicinal product) [SNOMED CT concept]
- Thymalfasin [MeSH Descriptor]
- Thymalfasin (substance) [SNOMED CT concept]
- thymalfasin [MeSH concept]
False automatic mappings
- thymosin alpha(1) (24-28) [MeSH concept]
- thymosin alpha(1) (24-28) [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing thymalfasin (medicinal product) [SNOMED CT concept]
- Thymalfasin [MeSH Descriptor]
- Thymalfasin (substance) [SNOMED CT concept]
- thymalfasin [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Thymalfasin/Dacarbazine [NCIt concept]

Keyword's position in hierarchy(ies) :

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