Preferred Label : Ginseng Compound;
NCIt definition : A compound containing the traditional Chinese medicine (TCM) ginseng, a herb belonging
to the Araliaceae family, with potential antioxidant, chemopreventive, anti-inflammatory
and antineoplastic activities. Upon administration of the ginseng compound, the active
ingredients, mainly ginsenosides, inhibit various signal transduction pathways that
play key roles in carcinogenesis and inflammation. This leads to the induction of
apoptosis in and inhibits proliferation of tumor cells. In addition, ginsenosides
enhance the activity of various antioxidant enzymes, induce nitric oxide (NO) formation,
inhibit the formation of reactive oxygen species (ROS) and protect against free radical-induced
DNA damage. Ginseng also modulates various components of the immune system, including
the activation of dendritic cells (DCs).;
NCI Metathesaurus CUI : CL503846;
Origin ID : C125000;
UMLS CUI : C4086361;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
