Ormaplatin - CISMeF

Preferred Label : Ormaplatin;

NCIt synonyms : Tetraplatin; tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))Platinum;

NCIt related terms : Platinum, tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))-;

NCIt definition : A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.;

UNII : SFK1SGY8V1;

InChIKey : QQDHPPCYXJYODE-RQDPQJJXSA-J;

CAS number : 62816-98-2;

Chemical formula : C6H14N2.4Cl.Pt;

NSC code : 363812;

Codes from synonyms : NSC0363812;

Details

Origin ID

C1250;

UMLS CUI

C0076329;

Currated CISMeF NLP mapping
- ormaplatin [MeSH concept]
- ormaplatin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ormaplatin [MeSH concept]
- ormaplatin [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- DNA Crosslinking [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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