Alpha-Actinin-1

Preferred Label : Alpha-Actinin-1;

NCIt synonyms : F-Actin Cross-Linking Protein; Actinin 1 Smooth Muscle; Non-Muscle Alpha-Actinin-1; Alpha-Actinin Cytoskeletal Isoform; ACTN1;

NCIt definition : Alpha-actinin-1 (892 aa, 103 kDa) is encoded by the human ACTN1 gene. This protein plays a role in F-actin crosslinking.;

Details

Origin ID

C124922;

UMLS CUI

C2351743;

Automatic exact mappings (from CISMeF team)
- Actinin, alpha-1 [OMIM gene]
- actinin alpha 1 [ORDO Gene]
OMIM relation
- Actinin, alpha-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ACTN1 protein, human [MeSH Supplementary Concept]
- ACTN1 protein, human [MeSH concept]
gene_encodes_gene_product
- ACTN1 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EF-Hand Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Adherens Junction Stabilization Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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