Preferred Label : Nitroglycerin/Sodium Citrate/Ethanol Solution;
NCIt synonyms : Glyceryl Trinitrate-Citrate-Ethanol; GTN-Citrate-Ethanol; NiCE; Nitroglycerin - Citrate - Ethanol;
NCIt definition : An antimicrobial lock solution (ALS) containing the nitrate nitroglycerin, sodium
citrate and ethanol, with potential antimicrobial and anticoagulant activities. Upon
application to the catheter as an ALS, the nitroglycerin is converted into nitric
oxide (NO), which exerts antimicrobial activity. The citrate exerts anticoagulant
activity, thereby preventing blood clotting and occlusion and maintaining the fluidity
of the administered solution. In addition, both citrate and ethanol exert antimicrobial
activity. This may prevent bacterial colonization on the surface of the catheter,
biofilm formation and prevents catheter-associated infections.;
NCI Metathesaurus CUI : CL502891;
Origin ID : C124659;
UMLS CUI : C4087029;
Semantic type(s)
- concept_is_in_subset
