Preferred Label : Ranitidine Hydrochloride/Bismuth Potassium Citrate/Sucralfate Hydrate Formulation;
NCIt synonyms : Ranitidine Hydrochloride/Bismuth Potassium Citrate/Sucralfate Hydrate;
NCIt definition : A formulation containing the hydrochloride salt form of the non-imidazole histamine
H2 receptor antagonist ranitidine, bismuth potassium citrate, and the hydrate form
of sucralfate, a basic aluminum complex of sulfated sucrose, with potential antacid,
radio- and cytoprotective activities. Upon oral administration of the ranitidine hydrochloride/bismuth
potassium citrate/sucralfate hydrate formulation, ranitidine binds to and blocks the
activity of the histamine H2 receptors in the parietal cells in the stomach and in
the gastrointestinal (GI) tract, thereby decreasing acid secretion. Sucralfate physically
binds to the surface of damaged mucosa, thereby forming a protective barrier that
shields the GI tract from stomach acid. It also neutralizes stomach acid. Bismuth
inhibits peptic activity, increases mucosal secretions and acts as a barrier to prevent
damage by acid. Altogether, this protects against ulcer formation and may help to
heal existing ulcers.;
Drug name : Albis;
NCI Metathesaurus CUI : CL502877;
Origin ID : C124645;
UMLS CUI : C4086763;
Semantic type(s)
- concept_is_in_subset
