" /> Isolated Ossification Site - CISMeF





Preferred Label : Isolated Ossification Site;

NCIt definition : An ossification site not localized to the main ossification area, as indicated by staining, but is still considered to be within the margins of a normal bone precursor.;

Alternative definition : CDISC: Ossification site within the margins of a normal bone precursor but separated from the main ossified (alizarin red stained) area. Does not imply any change to the bone precursor. (Makris S, Solomon HM, Clark R, Shiota K, Barbellion S, Buschmann J, Ema M, Fujiwara M, Grote K, Hazelden KP, Hew KW, Horimoto M, Ooshima Y, Parkinson M, Wise LD. Terminology of developmental abnormalities in common laboratory mammals (Version 2). Part B. Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):227-327.);

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07/05/2025


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