Preferred Label : Anti-CD133-CAR Vector-transduced Allogeneic T Lymphocytes;
NCIt synonyms : Allogeneic CART133; Allogeneic Anti-CD133 CAR T Cells;
NCIt definition : A preparation of allogeneic peripheral blood T-lymphocytes (PBTL) that have been genetically
modified to express a chimeric antigen receptor (CAR) specific for the chimeric CD
(cluster of differentiation) 133 antigen receptor, with potential immunostimulating
and antineoplastic activities. Upon administration, anti-CD133-CAR vector-transduced
allogeneic T-lymphocytes specifically recognize and kill CD133-expressing tumor cells.
CD133, a tumor associated antigen (TAA), is overexpressed on a variety of tumor cell
types.;
NCI Metathesaurus CUI : CL502528;
Origin ID : C124132;
UMLS CUI : C4085961;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
