Lipid Hydroperoxide

Preferred Label : Lipid Hydroperoxide;

NCIt synonyms : ROOH; LOOH; HO2R; LPO;

NCIt definition : Highly reactive, non-radical peroxols comprised of a fatty acid modified by a hydroperoxide group (-OOH) that are produced by lipid peroxidation. Lipid hydroperoxides are formed by sequential abstraction of allylic hydrogens from unsaturated fatty acids, which occurs in the presence of reactive oxygen species. These modified lipids can be further modified to create cytotoxic reactive aldehydes, such as malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE). Lipid hydroperoxide levels can be measured to assess the extent of oxidative stress.;

ChEBI ID : CHEBI:61051;

Details

Origin ID

C124072;

UMLS CUI

C0023776;

Automatic exact mappings (from CISMeF team)
- Lactoperoxidase [OMIM gene]
- lateral preoptic nucleus [UBERON concept]
- lipid hydroperoxide [Artificial nutrition thesaurus concept]
- lipid peroxides [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- lipid peroxides [MeSH Descriptor]
- lipid peroxides [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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