Childhood Gastrointestinal Stromal Tumor

Preferred Label : Childhood Gastrointestinal Stromal Tumor;

NCIt synonyms : Childhood GIST;

NCIt related terms : Gastrointestinal Stromal Tumor (GIST);

NCIt definition : A gastrointestinal stromal tumor (GIST) occurring in childhood. Pediatric GISTs differ biologically from adult GISTs in that only 11% of pediatric GISTs have activating mutations of KIT and PDGFRA.;

Alternative definition : NICHD: A gastrointestinal stromal tumor occurring during childhood. Pediatric GIST differ biologically from adult GIST in that only 11% of pediatric GIST have activating mutations of KIT and PDGFRA.;

Neoplastic status : Undetermined;

Details

Origin ID

C123906;

UMLS CUI

C4086159;

Automatic exact mappings (from CISMeF team)
- Gastrointestinal stromal tumor (disorder) [SNOMED CT concept]
- gastrointestinal stromal tumors [MeSH Descriptor]
Disease excludes normal cell origin
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
Validated automatic mappings to NTBT
- Gastrointestinal stromal tumor [ORDO Disease]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
disease_has_finding
- Childhood Lesion [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Interstitial Cell of Cajal [NCIt concept]
- Stromal Cell [NCIt concept]
disease_has_normal_tissue_origin
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_mapped_to_gene
- KIT Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 14 [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 22 [NCIt concept]
disease_may_have_molecular_abnormality
- KIT Gene Mutation [NCIt concept]
- PDGFRA Gene Mutation [NCIt concept]

Keyword's position in hierarchy(ies) :

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