Preferred Label : Cromolyn Sodium Inhalant PA101;
NCIt synonyms : Sodium Cromoglicate Inhalant PA10;
NCIt definition : A solution containing a high concentration of cromolyn sodium, with potential mast
cell stabilizing, anti-tussive and anti-inflammatory activities. Upon inhalation of
PA101 via a nebulizer, cromolyn blocks calcium ion influx into mast cells, thereby
preventing the degranulation of mast cells in the lungs. This blocks the release of
pro-inflammatory mediators from mast cells, such as histamine and slow-reacting substance
of anaphylaxis (SRS-A), and prevents both bronchoconstriction and an inflammatory
response. In indolent systemic mastocytosis (ISM), PA101 may be able to reduce the
symptoms associated with this disease;
Molecule name : PA101; PA 101;
NCI Metathesaurus CUI : CL498212;
Origin ID : C123818;
UMLS CUI : C4085208;
Semantic type(s)
- concept_is_in_subset
