Preferred Label : Staurosporine;
NCIt synonyms : Antibiotic AM 2282; Antibiotic 230; 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-,
(8alpha,9beta,10beta,12alpha)-( )-; (9alpha,10beta,11beta,13alpha)-( )-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one;
NCIt definition : A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer
activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including
protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI);
Alternative definition : NCI-GLOSS: A drug that belongs to the family of drugs called alkaloids. It is being
studied in the treatment of cancer.;
UNII : H88EPA0A3N;
InChIKey : HKSZLNNOFSGOKW-FYTWVXJKSA-N;
CAS number : 62996-74-1;
Molecule name : AM-2282; CGP-39360;
Chemical formula : C28H26N4O3;
NSC code : 618487;
ChEBI ID : CHEBI:15738;
Codes from synonyms : NSC0618487; 01722; CDR0000044852;
Origin ID : C1237;
UMLS CUI : C0075193;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
