" /> Staurosporine - CISMeF





Preferred Label : Staurosporine;

NCIt synonyms : Antibiotic AM 2282; Antibiotic 230; 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-( )-; (9alpha,10beta,11beta,13alpha)-( )-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one;

NCIt definition : A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI);

Alternative definition : NCI-GLOSS: A drug that belongs to the family of drugs called alkaloids. It is being studied in the treatment of cancer.;

UNII : H88EPA0A3N;

InChIKey : HKSZLNNOFSGOKW-FYTWVXJKSA-N;

CAS number : 62996-74-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 62996-74-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : AM-2282; CGP-39360;

Chemical formula : C28H26N4O3;

NSC code : 618487;

ChEBI ID : CHEBI:15738;

Codes from synonyms : NSC0618487; 01722; CDR0000044852;

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15/05/2024


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