Spiroplatin - CISMeF

Preferred Label : Spiroplatin;

NCIt synonyms : Cis-1,1-diamino-methylcyclohexane sulfato-platinum; Platinum, (1,1-cyclohexanedimethanamine-n,n')(sulfato(2-)-O,O')-, (sp-4-2)-;

NCIt definition : A synthetic derivative of cyclohexane sulfatoplatinum with antineoplastic properties. Spiroplatin induces DNA cross-links, thereby inhibiting DNA replication and RNA and protein synthesis. Similar to other platinum compounds, this agent has been shown to be mutagenic and carcinogenic. (NCI04);

UNII : H2V318W7LE;

InChIKey : XASGSSXPZXRXFL-UHFFFAOYSA-L;

CAS number : 74790-08-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 74790-08-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : TNO-6;

Chemical formula : C8H18N2.O4S.Pt;

NSC code : 311056;

Codes from synonyms : NSC0311056;

Details

Origin ID

C1234;

UMLS CUI

C0075022;

Currated CISMeF NLP mapping
- [cyclohexane-1,1-diylbis(methylamine)-n,n'][sulphato(2-)-o,o']platinum [Substance BNPC]
- spiroplatin [MeSH concept]
- spiroplatin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- [cyclohexane-1,1-diylbis(methylamine)-n,n'][sulphato(2-)-o,o']platinum [Substance BNPC]
- spiroplatin [MeSH concept]
- spiroplatin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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