Preferred Label : Allogeneic BK-specific Cytotoxic T-lymphocytes;
NCIt synonyms : Allogeneic BK-CTLs; Allogeneic BK-specific CTLs;
NCIt related terms : Allogeneic BK-specific Cytotoxic T Lymphocytes;
NCIt definition : Allogeneic cytotoxic T-lymphocytes (CTLs) that are specifically reactive to BK virus
(BKV), with potential antiviral activity. Upon infusion of allogeneic BK-specific
CTLs into immunocompromised patients who were infected with BKV after allogeneic stem
cell transplantation, these cells exert a specific CTL response against BKV, thereby
killing and eliminating the BKV-infected cells. BKV is a member of the polyomavirus
family that may cause mild symptoms in normal, healthy people; however, BKV infection
can lead to severe disease in immunocompromised patients.;
Origin ID : C123277;
UMLS CUI : C4055480;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
