Preferred Label : Amilomer;
NCIt synonyms : Starch Microspheres; Spherex;
NCIt definition : A synthetic microsphere formulation with arterial occlusive properties. Amilomer,
a product produced by partially hydrolyzing starch and epichlorohydrin, contains degradable
starch microspheres (DSM) with a diameter size of 45 micrometers that are readily
degraded by amylase. When used in transcatheter arterial chemoembolization (TACE)
procedures, infusion leads to lodging of the microspheres in the precapillary vessels
and, consequently, to the occlusion of the hepatic artery. Local occlusion of selected
blood vessels in conjunction with intrahepatic chemotherapy administration, results
in elevated intracellular hepatocyte drug concentrations and enhances localized cytotoxicity
against hepatic tumor lesions.;
CAS number : 82643-48-9;
Origin ID : C1231;
UMLS CUI : C1524076;
Automatic exact mappings (from CISMeF team)
- spherex [MeSH Supplementary Concept]
- Semantic type(s)
- concept_is_in_subset
