" /> Sodium Thiosulfate - CISMeF





Preferred Label : Sodium Thiosulfate;

NCIt synonyms : Sodium Thiosulphate; Sodium Thiosulfate Pentahydrate; Disodium Thiosulfate; Sodium Hyposulfate;

NCIt related terms : S-Hydril; Thiosulfate, Sodium, Pentahydrate; Thiosulfuric acid disodium salt;

NCIt definition : A water soluble salt and reducing agent that reacts with oxidizing agents. Although its exact mechanism of action is unknown, thiosulfate likely provides an exogenous source of sulfur, thereby hastening the detoxification of cyanide through the enzyme rhodanese (thiosulfate cyanide sulfurtransferase) which converts cyanide to the relatively nontoxic, excretable thiocyanate ion. In addition, this agent neutralizes the reactive alkylating species of nitrogen mustard, thereby decreasing skin toxicity related to nitrogen mustard extravasation. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is used in medicine as an antidote to cyanide poisoning and to decrease side effects of the anticancer drug cisplatin.;

UNII : HX1032V43M;

InChIKey : PODWXQQNRWNDGD-UHFFFAOYSA-L;

CAS number : 10102-17-7;

Drug name : Cyanide Antidote Package; Sodothiol; S-Hydril;

Chemical formula : 2Na.O3S2.5H2O;

NSC code : 45624;

ChEBI ID : CHEBI:32150;

Codes from synonyms : NSC0045624; CDR0000350247; 01941; 20162;

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02/06/2025


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