MARCKS wt Allele

Preferred Label : MARCKS wt Allele;

NCIt synonyms : MAC; MRACKS; Myristoylated Alanine-rich Protein Kinase C Substrate wt Allele; PRKCSL; PKCSL; MACS; Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS, 80K-L) Gene;

NCIt definition : Human MARCKS wild-type allele is located in the vicinity of 6q21 and is approximately 6 kb in length. This allele, which encodes myristoylated alanine-rich C-kinase substrate protein, is involved in the crosslinking of actin filaments and may be involved in cell motility, phagocytosis, membrane trafficking, and mitogenesis.;

GenBank Accession Number : NM_002356;

Details

Origin ID

C122754;

UMLS CUI

C4049728;

Automatic exact mappings (from CISMeF team)
- Active C5b6789 (substance) [SNOMED CT concept]
- Colobomatous microphthalmia [ORDO Disease]
- Complement membrane attack complex (C5b-C6-C7-C8-C9n) [LOINC component]
- Myristoylated alanine-rich protein kinase C substrate [OMIM gene]
- Raincoat (physical object) [SNOMED CT concept]
- complementary therapies [MeSH Descriptor]
- membrane attack complex [GO term]
- mitochondrion-associated adherens complex [GO term]
False automatic mappings
- Macrocephaly – alopecia – cutis laxa – scoliosis syndrome [ICD-11 More detail]
OMIM relation
- Myristoylated alanine-rich protein kinase C substrate [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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