Preferred Label : Wnt Signaling Inhibitor SM04755;
NCIt definition : An orally bioavailable small molecule inhibitor of the Wnt signaling pathway, with
potential antineoplastic activity. Upon oral administration, Wnt signaling inhibitor
SM04755 targets and binds to an as of yet undisclosed target in the Wnt signaling
pathway, thereby preventing Wnt-mediated signaling. This may inhibit growth of tumor
cells in which the Wnt signaling pathway is overactivated. The Wnt signaling pathway
is upregulated in many cancers and plays a key role in tumor cell proliferation.;
Molecule name : SM04755;
NCI Metathesaurus CUI : CL474102;
Origin ID : C122693;
UMLS CUI : C4053589;
Semantic type(s)
- concept_is_in_subset
