Preferred Label : Carbon C 11 Sarcosine;
NCIt synonyms : 11C-sarcosine; 11C-labeled Sarcosine;
NCIt definition : A radiotracer consisting of sarcosine, the N-methyl derivative of the amino acid glycine,
labeled with the positron-emitting isotope carbon C 11, that can be used for tumor
imaging upon positron emission tomography/computed tomography (PET/CT). Upon administration,
C-11 sarcosine is taken up by and accumulates in tumor cells, thereby allowing tumor
imaging with PET/CT. Sarcosine, a non-proteinogenic amino acid and oncometabolite,
is elevated in certain tumor cell types. Its expression seems to correlate with increased
tumor invasiveness.;
Origin ID : C122684;
UMLS CUI : C4055275;
Semantic type(s)
concept_is_in_subset