Atamestane - CISMeF

Preferred Label : Atamestane;

NCIt definition : A synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. Atamestane blocks the production of the hormone estrogen in the body. It belongs to the family of drugs called antiestrogens.;

UNII : 62GA3K28B6;

InChIKey : PEPMWUSGRKINHX-TXTPUJOMSA-N;

CAS number : 96301-34-7;

Chemical formula : C20H26O2;

Codes from synonyms : CDR0000045002; 31637;

Details

Origin ID

C1224;

UMLS CUI

C0074442;

Currated CISMeF NLP mapping
- atamestane [MeSH concept]
- atamestane [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- atamestane [MeSH concept]
- atamestane [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Atamestane/Toremifene [NCIt concept]

Keyword's position in hierarchy(ies) :

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