Preferred Label : Diphtheria-Tetanus-Acellular Pertussis-Inactivated Poliomyelitis-Haemophilus influenzae
Type B Vaccine;
NCIt synonyms : DTaP(5)-IPV-Hib; DTaP-IPV-Hib;
NCIt definition : A vaccine consisting of detoxified diphtheria toxoid (D), detoxified tetanus toxoid
(T), acellular pertussis (aP) antigens, inactivated poliovirus (IPV) types 1, 2 and
3, and Haemophilus influenzae type b (Hib) capsular polysaccharide (polyribosylribitol
phosphate; PRP) covalently bound to tetanus protein, suspended in water for injection
and with active immunizing activity against diphtheria, tetanus, pertussis, poliomyelitis
and H. influenzae type b. The five purified pertussis antigens in this vaccine are
pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin (PRN) and fimbriae
types 2 and 3 (FIM). Upon intramuscular injection of the diphtheria-tetanus-acellular
pertussis-inactivated poliomyelitis-Haemophilus influenzae type b vaccine (DTaP-IPV-Hib),
this vaccine activates the immune system to develop antibodies against diphtheria
toxin, tetanus toxin, B. pertussis antigens, polioviruses and Hib, thereby providing
active immunization against these diseases. The diphtheria and tetanus toxoids and
pertussis antigens (inactivated PT, FHA, PRN and FIM) are adsorbed separately onto
aluminum phosphate and then combined with IPV and PRP.;
Drug name : Pediacel;
Origin ID : C122399;
UMLS CUI : C2716396;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
