Preferred Label : Autologous Dendritic Cell Vaccine ACT2001;
NCIt synonyms : Autologous DC Vaccine ACT2001;
NCIt definition : A cell-based cancer vaccine composed of autologous, immature dendritic cells (DCs),
with potential immunostimulating and antineoplastic activities. Upon leukapheresis,
immature DCs are isolated and re-administered intra-tumorally. The immature DCs internalize
and process the tumor-associated antigens (TAAs), migrate to the lymphatic system,
and then expose the immune system to the TAAs. This induces a specific cytotoxic T-lymphocyte
(CTL) response against the cancer cells leading to tumor cell lysis.;
Molecule name : ACT2001;
Origin ID : C121856;
UMLS CUI : C4053686;
Semantic type(s)
- concept_is_in_subset
