Preferred Label : Cocoa Extract;
NCIt synonyms : Cocoa Extract Supplement;
NCIt related terms : COCOA;
NCIt definition : A dietary supplement containing cocoa extract derived from the cacao bean, with potential
vasodilating, anti-inflammatory, cardiovascular protective, neuroprotective, cognition
enhancing and chemopreventive activities. Cocoa extract contains flavonoids, including
high levels of epicatechin, catechin, procyanidins and xanthines, such as theobromine.
Upon oral administration, the bioactive ingredients in the cocoa extract inhibit angiotensin-converting
enzyme (ACE) and increase the production of nitric oxide (NO) through the activation
of endothelial nitric oxide synthase (eNOS). This causes vasodilation, improves blood
flow, and decreases blood pressure. The cocoa extract also improves insulin sensitivity,
enhances cognition, and decreases the production of pro-inflammatory molecules. In
addition, this extract exerts antioxidant effects and is able to scavenge reactive
oxygen species (ROS). As a result, healthy cells are protected from oxidative stress
and DNA damage.;
UNII : D9108TZ9KG;
Origin ID : C121851;
UMLS CUI : C1138626;
Semantic type(s)
- concept_is_in_subset
