Preferred Label : Autologous NSCLC Peptide-specific Dendritic Cell Vaccine;
NCIt synonyms : Autologous NSCLC Peptide-specific DC Vaccine;
NCIt definition : A personalized cell-based cancer vaccine composed of autologous dendritic cells (DCs)
pulsed with immunogenic peptides derived from autologous non-small cell lung cancer
(NSCLC) cells, with potential immunostimulating and antineoplastic activities. During
leukapheresis, mature DCs are loaded with autologous NSCLC-derived peptides. Upon
re-administration of the NSCLC peptide-specific DC vaccine, the immune system is exposed
to NSCLC-associated antigens. This results in the induction of a specific cytotoxic
T-lymphocyte (CTL) response against NSCLC cells and tumor cell lysis.;
Origin ID : C121848;
UMLS CUI : C4055423;
Semantic type(s)
- concept_is_in_subset
