" /> Mivebresib - CISMeF





Preferred Label : Mivebresib;

NCIt synonyms : Ethanesulfonamide, N-(4-(2,4-difluorophenoxy)-3-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo(2,3-C)pyridin-4-yl)phenyl)-;

NCIt definition : An inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, mivebresib binds to the acetyl-lysine binding site of BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors.;

UNII : VR86R11J7J;

InChIKey : RDONXGFGWSSFMY-UHFFFAOYSA-N;

CAS number : 1445993-26-9;

Molecule name : ABBV-075;

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18/06/2025


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