Preferred Label : Chlorhexidine/Ethyl Alcohol Mouthwash;
NCIt synonyms : Chlorhexidine/Ethyl Alcohol Mouth Rinse;
NCIt definition : A mouthwash containing the biguanide chlorhexidine and ethyl alcohol, with topical
antibacterial activity. Upon rinsing the oral cavity with the chlorhexidine/ethyl
alcohol mouthwash, the positively charged chlorhexidine cation exerts its antibacterial
activity through binding to the negatively charged microbial cell surface, which destroys
the integrity of the cell membrane. This causes leakage of intracellular components
leading to cell death. Ethyl alcohol denatures bacterial proteins, and dissolves and
disrupts the bacterial lipid membrane, thereby killing the bacteria. This reduces
oral colonization with harmful bacteria and may prevent oral mucositis.;
Drug name : ChloraPrep;
Origin ID : C121780;
UMLS CUI : C4055241;
Semantic type(s)
- concept_is_in_subset
