Preferred Label : Allogeneic Mesothelioma Tumor Lysate-pulsed Autologous Dendritic Cell Vaccine;
NCIt synonyms : Allogeneic Mesothelioma Tumor Lysate-pulsed Autologous DC Vaccine; MesoCancerVac;
NCIt definition : A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with
a mixture of lysates from five allogeneic mesothelioma tumor cell lines, with potential
immunostimulatory and antineoplastic activities. Upon leukapheresis, DCs are loaded
with allogeneic mesothelioma tumor cell lysates. Upon re-administration of the allogeneic
mesothelioma tumor lysate-pulsed autologous DC vaccine, the immune system is exposed
to an undefined amount of mesothelioma-associated antigens, which stimulates the induction
of a specific cytotoxic T-lymphocyte (CTL) response against mesothelioma tumor cells
and leads to tumor cell lysis.;
Origin ID : C121640;
UMLS CUI : C4053747;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
