Preferred Label : Recombinant Super-compound Interferon;
NCIt synonyms : Recombinant Super Compound Interferon; rSIFN-co;
NCIt definition : A recombinant form of the naturally-occurring cytokine interferon-alpha (IFN-a) that
has a modified spatial configuration, with immunomodulating, antiviral and antineoplastic
activities. Upon administration of recombinant super-compound interferon (rSIFN-co),
this agent binds to IFN-specific cell surface receptors, resulting in the transcription
and translation of genes whose protein products have antiviral, antiproliferative,
anticancer, and immune-modulating effects. The 3-dimensional conformational change
improves efficacy and causes less side effects compared to IFN-a.;
Origin ID : C121542;
UMLS CUI : C4053486;
Semantic type(s)
concept_is_in_subset