Hypomethylation

Preferred Label : Hypomethylation;

NCIt synonyms : DNA Hypomethylation;

NCIt definition : An epigenetic process that either inhibits DNA methyltransferase activity or promotes DNA demethylase activity, and results in a net loss of 5-methylcytosines and a net gain of unmethylated cytosine nucleotides either in specific repetitive DNA sequences or across the bulk of the genome. This phenomenon is associated with aging, genomic instability and tumorigenesis.;

Details

Origin ID

C121521;

UMLS CUI

C2613367;

Automatic exact mappings (from CISMeF team)
- DNA hypomethylation [GO term]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- DNA hypomethylation [GO term]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
- Epigenetic Process [NCIt concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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