Preferred Label : Cannabis Extract Oil SR Capsule;
NCIt synonyms : Cannabis SR Capsules; Cannabis SR Capsule;
NCIt definition : A sustained-release (SR), oil-based oral capsule composed of a cannabis extract, which
contains a variety of cannabinoids but is comprised mainly of tetrahydrocannabinol
(THC), with potential anti-cachexic and analgesic activities. Upon oral administration,
the cannabinoids bind to the cannabinoid G-protein coupled receptor CB1, which is
located in both central and peripheral neurons; CB1 receptor activation inhibits adenyl
cyclase, increases various signal transduction pathways, and modulates the activity
of various ion channels. This provides an analgesic effect, increases appetite, decreases
chemotherapy-induced nausea and vomiting, and improves weight gain. The formulation
allows for the immediate release of cannabinoids and quick onset of action, which
is followed by a gradual release of cannabinoids. The SR form facilitates longer lasting
therapeutic effects and causes fewer psychoactive side effects when compared to non-SR
cannabinoid-containing oral formulations.;
Drug name : Cannabics SR;
Origin ID : C120551;
UMLS CUI : C4055277;
Semantic type(s)
- concept_is_in_subset
